Worldwide Healthcare


Rated Fund 2013-19. Invests in a diverse range of healthcare companies

This trust has twice been highly commended in the Best Large Trust category in Money Observer’s annual trust awards, no mean feat when it was up against more than 100 trusts from a variety of sectors. It invests in a diversified portfolio of worldwide pharmaceutical, biotechnology and healthcare equipment, technology and services companies.

Sven Borho, a founder partner of US-based specialist healthcare fund manager OrbiMed Capital, has run the trust since its inception in 1995. He was joined by co-manager Trevor Polischuk in 2017. They are supported by a team of 80 investment professionals who carry out extensive research to find potential investments.

The managers seek innovation and growth in the global healthcare industry and invest in healthcare companies that offer the greatest return potential. Risk is spread through global exposure and diversification across different healthcare sub-sectors.

At the end of 2018, pharmaceutical and biotech companies each accounted for 30% of the portfolio, which consisted of 90 holdings. The majority of the top 10 holdings were large, profitable companies, collectively accounting for 40% of assets. More than 75% was invested in US stocks, but there was also 10% in emerging markets, 9% in Europe and 6% in Asia.

Skerritts Wealth Management is a long-term supporter of the trust and points to its record as the best performer across the whole investment trust sector since 1995. Healthcare is a key theme in its portfolios given the defensive nature of the sector and the world’s ageing population.

The board operates an active discount management policy so shares in the trust typically trade around the value of underlying assets.

Narrative and ratings content all as of 01 January 2019.

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Worldwide Healthcare
Frostrow Capital LLP
Closed Ended Investment Company
Sector Specialist: Biotechnology & Healthcare
0.9 %
Risk Rating
3 Year Sharpe
3 Year Alpha
1 %
MSCI World Healthcare Net
Fund Size
£ 1.36 billion
Discount Premium
In order to achieve a high level of capital growth, the Company invests in the global healthcare sector and in a diversified portfolio of shares in pharmaceutical and biotechnology companies and related securities in the healthcare sector. It uses gearing, and derivative transactions to mitigate risk and also to enhance returns.
Holding %
Takeda Pharmaceutical Co Ltd 9.11 %
Boston Scientific Corp 7.07 %
Merck & Co Inc 5.70 %
Alexion Pharmaceuticals Inc 5.37 %
Novartis AG 4.33 %
Edwards Lifesciences Corp 3.30 %
Wright Medical Group NV 3.16 %
Vertex Pharmaceuticals Inc 3.14 %
Neurocrine Biosciences Inc 2.98 %
Novo Nordisk A/S B 2.90 %
Region %
United States 69.64 %
Japan 10.80 %
Europe - ex Euro 8.63 %
Asia - Emerging 6.14 %
Sector %
Healthcare 97.56 %
Frostrow Capital LLP
WC2A 1AL, London, United Kingdom
Legal Structure
Closed Ended Investment Company


Trevor Polischuk
Joined 03/31/2015

Polischuk joined OrbiMed in 2003 as an analyst covering the major global pharmaceutical industry. Previously, he worked at Lehman Brothers as a senior research analyst covering the U.S. pharmaceutical industry.

Sven Borho
Joined 02/01/2013

Sven H. Borho, CFA, is a founding General Partner of OrbiMed. Mr. Borho is a portfolio manager for OrbiMed’s public equity funds and he heads the firm’s trading efforts. He started his career in 1991 when he joined Mehta and Isaly as a Senior Analyst covering European pharmaceutical firms and biotechnology companies worldwide. In 1993, Mr. Borho became portfolio manager to investment funds under management. Mr. Borho studied business administration at Bayreuth University in Germany and received a M. Sc. (Econ.) from The London School of Economics; he is a citizen of both Germany and Sweden.

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